Community. Health. Fun.

Our 26.2 mile, 13.1 mile and half marathon relay courses, wind through Cape Girardeau, Missouri. The community and sponsor support results in an excellent race day experience for all participants.

The race's proceeds benefit local non-profits who improve the health and well-being of those who call Southeast Missouri home. Since the race's inception, over $40,000 has been donated to charities.

We believe that fitness equals happiness, and encourage our participants to challenge their bodies while maintaining a healthy lifestyle. 


Embrace the Race Theme


The Muddy River Marathon is more than just a race. It’s a unifying event that not only brings us together but also deepens and strengthens the roots of our community.


It is a journey that takes us past the river and beyond, far away from the concrete jungles of a big city, and allows us to truly experience the freedom and beauty that Southeast Missouri has to offer. The excitement of facing a challenge head-on and coming out stronger on the other side. It allows us to break free. It allows us to Run Wild.


A Medal Fit for a Wild Heart

Our new medal encapsulates this year’s “Run Wild” theme and will serve as a token to remember the challenge you faced and overcame.


\Wear it with pride once you cross the finish line and never forget the hard work and sacrifices you made to prove that you truly had what it took to Run Wild.


The Muddy River Marathon supports the Community Partnership of Southeast Missouri

The mission of the Community Partnership of Southeast Missouri is to maximize resources to develop and deliver a wide range of services that improve the lives of individuals, children, and families, and to build strong neighborhoods & communities.Thanks to our sponsors and participants, proceeds from the Muddy River Marathon are donated to the Community Partnership of Southeast Missouri.