Community. Health. Fun.

Our 26.2 mile, 13.1 mile and half marathon relay courses, wind through Cape Girardeau, Missouri. The community and sponsor support results in an excellent race day experience for all participants.

The race's proceeds benefit local non-profits who improve the health and well-being of those who call Southeast Missouri home. Since the race's inception, over $40,000 has been donated to charities.

We believe that fitness equals happiness, and encourage our participants to challenge their bodies while maintaining a healthy lifestyle. 



Embrace the Race Theme

2022's race theme, "Run Like the River", was brought to life in race swag, finisher medals, entertainment and more.

Like the current of a river, long-distance runners are strong and swift. “Run Like the River” is meant to inspire the runners and conjure up thoughts of the Mississippi, overlooking which they’ll begin and end their race.

Keep an eye our for 2023's theme which will be unveiled soon.


A Memorable Medal for

a Memorable Race

Finishers of the Muddy River Marathon to earn an annually designed, exclusive medal.

2023's all-new design will feature the race colors, a nod to the 2023 theme and carries your own unique memory of a race well run.

2022's medal is shown.


The Muddy River Marathon supports the Community Partnership of Southeast Missouri

The mission of the Community Partnership of Southeast Missouri is to maximize resources to develop and deliver a wide range of services that improve the lives of individuals, children, and families, and to build strong neighborhoods & communities.Thanks to our sponsors and participants, proceeds from the Muddy River Marathon are donated to the Community Partnership of Southeast Missouri.